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Why Scientists feel good about GABA

A naturally occurring brain chemical is responsible for controlling insomnia, irritability, anxiety and panic attacks.

Sleep aides such as Ambien and Sonata target the function of an important brain chemical known to quiet general brain activity and promote sleep. To avoid undesirable side effects of these and similar drugs, researchers have begun to focus on the GABA system to develop better treatment for insomnia.

Neuroscientist Candace Pert, Ph.D. discovered the existence of cell receptors in 1972, establishing that there are GABA receptor sites throughout the brain and central nervous system.

GABA (Gamma Amino Butyric Acid) is a naturally occurring chemical in the brain that is responsible for an upbeat mood, positive self-image, goodwill and sound sleep.

Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased science's understanding of various aspects of GABA-A receptors.¹

The most valid scientific research published on GABA relates to how it affects anxiety and stress impulses in the central nervous system. It has been suggested that a shortage of GABA in the brain may cause panic attacks, since an intake of tranquilizers can increase the level of GABA in the body.

Anti-anxiety medications such as the popular drugs Xanax, Valium and Ativan, are very effective because they also target GABA receptors in the brain.

GABA has been the subject of numerous studies on panic disorder as well as other psychiatric disorders and substance abuse conditions. In a study at Yale, people with panic disorder were found to have a 22% reduction in total occipital cortex GABA than people without panic disorder.²

When GABA and other vital neurotransmitters become depleted, the prefrontal cortex of the brain can become bombarded with anxiety-related messages. General anxiety is responsible for restlessness, irritability, insomnia, and even seizures.

Classified as an inhibitory neurotransmitter, GABA can be used to calm a person, much like tranquilizers, but without the possibility of addiction. GABA does not cause mania or psychosis, as do other mood enhancement treatments such as Prozac or Zoloft. Nor does it cause depletion or retention of serotonin as do those drugs.

Several neurological disorders, such as epilepsy, sleep apnea, and Parkinson’s disease are affected by this neurotransmitter.

GABA acts as a "balancer" for the brain, controlling the release of adrenaline and cortisol into the bloodstream.

At the Pain & Stress Center, we have a long record of patient success at easing anxiety, muscle pain/spasms, and nervous stomachs with GABA. The GABA 750 or 375 we use is free form, dissolves in water, is tasteless, odorless, and the calming results usually occur within seven minutes.

Nutrient deficiencies do change behavior. Human behavior involves the functioning of the whole nervous system, and the nervous system requires amino acids. GABA is vital for energy and smooth brain function.

¹An update on GABAA receptors
by Mehta AK, Ticku MK
Department of Pharmacology,
The University of Texas Health Science Center at San Antonio,
7703 Floyd Curl Drive, San Antonio, TX 78284-7764, USA.
Brain Res Brain Res Rev 1999 Apr; 29(2-3):196-217

²Reference: Goddard AW, Mason GF, Almai A, Rothman DL, Behar KL, Petroff OAC, Charney DS, Krystal JH (2001). Reductions in the occipital cortex GABA levels in panic disorder detected with ^{1H-Magnetic Resonance Spectroscopy. Arch Gen Psychiatry 58: 556-561.}
 

†These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, cure, treat, or prevent any disease.

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